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The primary study outcome is self-reported insomnia severity at 6 weeks, measured with the Insomnia Severity Index (ISI) in an intention to treat analysis.. Remeron might be more likely to cause weight gain than some of the other antidepressant options. Therefore, mirtazapine was administered at a low daily dose of 7. After this period the effects of the remerom where causeing anxiety soon after dosing so I discontinued. Not surprisingly, this can lead to weight gain in some people. While the dosage will likely start as small as 15 mg during the initial weeks, this dose can gradually increase to around 45 mg over time. At higher doses, the antihistamine activity is offset by increased noradrenergic transmission, which reduces its sedating effect. Mirtazapine 15 mg impaired road-tracking task and SSS Mirtazapine at low doses also has a high affinity for the histamine-1 receptor. It might specifically increase your cravings for carbohydrates. 023, respectively) Conclusions: Mirtazapine 7. But I have gained weight, about 25 lbs this past yr. 11 days later (yesterday)all hell broke loose As a result, I went back on antidepressants escitalopram (10 mg), klonopin (0. 5 mg series, 15 mg of mirtazapine was additionally administered on day 9, followed by all the same assessments on day 10. 5 mgin the present case All participants start and end with single dose, but dose can be doubled following GP consultation in week 3. 023, respectively) In the mirtazapine 7. Recommended Dosage The recommended starting dose of REMERON/REMERONSolTab is 15 mg once daily, administered orally, preferably in the evening prior to sleep. For depression it is recommended to take Remeron once daily. 75 to 4 mg nightly for sleep & aid with benzo withdrawal. 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